Simplex's clientele consists primarily of international companies from all over the world, among of which:
- Big financial institutions and banks
- Investment and forex firms
- Companies from the oil and energy industry
- Big manufacturing companies
- Corporate services and fiduciary providers
- Companies from the security industry
- Internet Service Providers (ISPs)
- Shipping companies
- Software companies
- Broadcasting and media companies.

We also, serve many smaller clients who either wish to avoid the hassle and cost of in-house infrastructure and personnel or, despite of being small, they are serious about their data and systems.